This is the list of Actors from the cast Sanford and Son television series.
- Redd Foxx - starred in the title role as Fred Sanford
- Demond Wilson - appeared in the co-starring role as "Dummy" son Lamont Sanford
- LaWanda Page - co-starred as Aunt Esther in seasons 2-6
- Whitman Mayo - played Grady Wilson, Fred's best friend
- Don Bexley - appeared as "Bubba" Bexley Fred's loyal, but sometimes dim-witted friend
- Nathaniel Taylor - appeared as Lamont's best friend Rollo Lawson
- Lynn Hamilton - appeared as Fred's girlfriend, Nurse Donna Harris
- Noam Pitlik - appeared as LAPD Officer "Swanny" Swanhouser in season 1
- Hal Williams - appeared as LAPD Officer "Smitty" Smith in season 1-6
- Howard T. Platt - appeared as LAPD Officer "Hoppy" Hopkins in season 1-6
- Marlene Clark - played Janet Lawson, Lamont's steady girlfriend and fiancee in seasons 5 & 6
- Gregory Sierra - appeared as Julio Fuentes in seasons 1-4
- Raymond Allen - replaced DeForest Covan as Uncle Woodrow "Woody" Anderson in season 2, remaining thru season 6
- Pat Morita - appeared as Ah Chew in seasons 3 - 5
- Nancy Kulp - appeared as May Hopkins, Officer Hopkins's mother
- Eric Laneuville - appeared as Daniel Anderson in seasons 5-6
- Ernest "Skillet" Mayhand - appeared as Skillet in season 2 and 3
- Leroy Daniels - appeared as Leroy in season 2 and 3
- Arnold Johnson - appeared as Hutch in season 4 and 5
- George Wiltshire - appeared as Elroy in season 5